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San Francisco, United StatesView on map

Hotel Spero

Boutique Heritage Luxury in the Heart of San Francisco

Hotel Spero logo

Experience boutique luxury in the heart of San Francisco’s thriving Tenderloin neighbourhood with an enriching stay at Hotel Spero. Housed in a historical Spanish Colonial design masterpiece, Hotel Spero is within walking distance to the most sought-after central city attractions including Union Square, Transamerica Pyramid, the San Fransisco Cable Car Museum and endless noteworthy stores and restaurants.

Inside, you’ll find the perfect fusion of vintage opulence and modern elegance from the historic grand lobby to the top-of-the-line fitness centre. After a day of exploring the city, mill over innovative American cuisine or end the evening with handcrafted cocktails and locally brewed beers at Jasper’s Corner Tap & Kitchen — an upscale gastropub known for its elegant yet easy-going setting.

1 to 30 Nights packages available
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4.7/5
(3K reviews)
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Location

Hotel Spero
405 Taylor Street, San Francisco, California, United States, 94102

Perfectly located in the Tenderloin, Hotel Spero has the best of the city on its doorstep. You’ll find yourself within a stone’s throw of the city’s shopping and restaurant scene, as well as city landmarks including Union Square, Ferry Building and the San Fransisco Flower Market (10-20-minute walk).

The hotel is located approximately a 25-minute drive from San Francisco International Airport (SFO). Airport transfers are not included in your package, please plan accordingly.

Need flights? Our dedicated flights concierge can assist with all your flight requirements. Contact sales@luxuryescapes.com.

Facilities

Fine Print

Package Inclusions: Inclusions are correct at the time of purchase. Refer to your booking confirmation for details. Please note package inclusions for extra guests vary depending on the rate selected, please choose your package carefully.

Dining inclusions do not include drinks (unless otherwise stated). Menus are subject to change without notice.

Important: The hotel, transportation and/or destination you are travelling to may have health, insurance and vaccination requirements in place. Please ensure you stay up to date with any requirements prior to your departure.

The property, facilities and dining are subject to government regulations and restrictions. Please check the property website for the most up-to-date information as some of the services may be impacted.

Treat Me reserves the right to modify prices for marketing and commercial reasons. Please note that full terms and conditions apply.

LuxPlus+ Terms & Conditions:

  • LuxPlus+ pricing and bonus inclusions apply to LuxPlus+ members only. Please ensure you are signed into the account associated with your LuxPlus+ membership while booking.
  • Bonus inclusions will be automatically applied during checkout when you make a booking with a participating hotel using the account associated with your LuxPlus+ membership.
  • Please note: Bonus inclusions vary depending on the participating hotel. Please refer to your package inclusions upon checkout/purchase to confirm the bonus inclusions associated with your booking.
  • Bonus inclusions are only available when the LuxPlus+ member is the primary traveller on the booking.
  • LuxPlus+ bonus inclusions are not available for bookings made back-to-back (separate bookings for consecutive nights’ stay) at the same hotel. In the instance of back-to-back bookings at the same hotel being made, you will only receive the included benefits once.

LuxPlus+ benefits will not be awarded in relation to any purchases, transactions or non-transactional actions that are reversed, cancelled and/or refunded.

LuxPlus+ member discounts and bonus inclusions cannot be converted or exchanged for cash.

Luxury Escapes reserves the right to review all bookings and bonus inclusions to ensure compliance with LuxPlus+ terms and conditions.

LuxPlus+ member pricing cannot be combined with any other promotions, offers or discount codes unless explicitly stated by Luxury Escapes.

To receive member-only pricing, discounts, early access and bonus inclusions, sign up to LuxPlus+. Learn more here.

Reviews

8.0
Very Good
Reviews from Google
Pat D.
Reviewed 08 Aug 2025
10
I can't say enough good things about Hotel Spero. We are in the entertainment business and we spend a lot of time in Bay Area hotels. When we work in San Francisco, Hotel Spero is like our second home. The hotel is one of two IHG Vignette hotels located in the U.S. It's in a beautifully restored historic high-rise building in the old "Tenderloin" area. The lobby is a site to behold. The staff has always been kind and accommodating. The rooms are lovely and comfortable. The high floor suites have great views of the city and are much more spacious than the standard rooms, so we like them the best. The hotel is located a short Uber or Waymo from lots of fun things to do, or for us, many of our SF work locations. The only downside, which is the same wherever you go in San Francisco is the cost of parking your car. The garage next to the hotel is $50/night. There are several garages within a block or two that cost a little less. If you've visiting SF, please consider staying at Hotel Spero. You will not regret it.
Recommends this hotel
10
Ricia E.
Reviewed 06 Aug 2025
10
Fantastic stay here , we traveled all the way from Sydney , didn’t have such a good start at the first hotel we check into managed to get a last minute booking here ! So accomodating and really turned a not so nice experience in to a fantastic one ! Staff at the front desk were superb , every single one of them ! Room service , attentive and freshened up our room daily , so good !! Food and Beverage in Jaspers was superb but the standout for us was the staff in Jaspers , in particular Maria ! What a wonderful human being , going above and beyond . They were busy there but kept on top of the service with a smile . Thank you Hotel Spero! What a fantastic team You have here , You have made our stay here so special an memorable . Many many thanks . The Datsuns x
Recommends this hotel
10
Tina K.
Reviewed 09 Aug 2025
8.0
Nice!
Recommends this hotel
8.0
Magali G.
Reviewed 30 Jul 2025
8.0
I recently stayed at Hotel Spero and had a pleasant experience overall. The hotel and rooms appear to have been recently remodeled—everything looked fresh, clean, and well-maintained. The staff was friendly and helpful, and I appreciated how calm and quiet the hotel was throughout my stay. While the surrounding neighborhood didn’t feel particularly inviting, I felt reassured knowing there was a doorman or security guard at the entrance during the evening hours. That extra sense of security was a nice touch. Overall, a solid stay if you’re looking for a clean, comfortable, and affordable hotel in the area.
Recommends this hotel
8.0
Reviews: 1-4 of 4
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